Catherine Duclos, Ph.D.

Associate Professor of research (2022- )
Department of anesthesiology and pain medicine, Université de Montréal
catherine.duclos@mail.mcgill.ca

Training

Postdoctoral fellowship in computational neurosciences computationnelles and consciousness (McGill University)
Ph.D. in biomedical sciences (Université de Montréal)

Research interests

To characterize the functional neural networks of different states of consciousness (e.g. anesthesia, sleep, coma, delirium, disorders of consciousness) and to understand how these networks can be modulated in order to improve the cognitive and functional health of patients in surgical and critical care.

Methodological approaches

Electroencephalography, functional connectivity, graph theory, pharmacological neuromodulation, closed-loop neuromodulation.

Fundings

Description

My team

Karine Lacourse, Ing., M.Sc.

Software Developer

David Lévesque, Ing.

Software Developer

Selected publications

Duclos C, Mahdid Y, Nadin D, Maschke C, Rokos A, Abour C, Badawy M, Létourneau J, Owen AM, Plourde G, Blain-Moraes S. Anesthetic-induced reconfiguration of brain networks predicts consciousness recovery in unresponsive patients. Soumis.

Duclos C*, Nadin D*, Mahdid Y, Tarnal V, Picton P, Vanini G, Golmirzaie G, Janke E, Avidan MS, Kelz MB, Mashour GA, Blain-Moraes S. Brain network motifs are markers of loss and recovery of consciousness. Scientific Reports. Révisions demandées.

Duclos C, Norton L, Laforge G, Frantz A, Maschke C, Badawy M, Letourneau J, Slessarev M, Gofton T, Debicki D, Owen AM, Blain-Moraes S. Protocol for the prognostication of consciousness recovery following a brain injury. Frontiers in Human Neuroscience. 2020;14:582125.

Nadin D, Duclos C, Mahdid Y, Rokos A, Badawy M, Letourneau J, Arbour C, Plourde G, Blain-Moraes S. Brain Network Motif and Hub Topology Predicts Emergence from Disorders of Consciousness. Neuroscience of Consciousness. 2020;2020(1):niaa017.

Duclos C, Dumont M, Paquet J, Blais H, Van der Maren S, Menon DK, Bernard F, Gosselin N. Sleep-wake disturbances in hospitalized patients with traumatic brain injury: association with brain trauma but not with an abnormal melatonin circadian rhythm. SLEEP. 2020;43(1):1-8. doi:10.1093/sleep/zsz191

Duclos C, Dumont M, Arbour C, Paquet J, Blais H, Menon DK, De Beaumont L, Bernard F, Gosselin N. Parallel recovery of consciousness and sleep in acute traumatic brain injury. Neurology. 2017;88(3):268-275.

Projects

Use of anesthesia to detect the potential for consciousness recovery in non-communicative patients

Development of prognostic markers of consciousness recovery following brain injury

Closed-loop stimulation of slow oscillations in anesthesia

Exploration of the criticality of neural networks in different states of consciousness